CORRESP 1 filename1.txt FRANKLIN TEMPLETON INVESTMENTS ONE FRANKLIN PARKWAY SAN MATEO, CA 94403-1906 December 12, 2007 Filed Via EDGAR (CIK # 0000872625) Securities and Exchange Commission Judiciary Plaza 100 F Street, NE Washington, D.C. 20549 Re: FRANKLIN STRATEGIC SERIES ("Registrant") Franklin Focused Core Equity Fund File Nos. 033-39088 & 811-06243 Ladies/Gentlemen: In response to comments received on our filing of Post-Effective Amendment No. 52 under the Securities Act of 1933, as amended, and Amendment No. 54 under the Investment Company Act of 1940, as amended, to the Registrant's Registration Statement on Form N-1A, filed pursuant to Rule 485(a) under the Securities Act of 1933, as amended, on September 28, 2007, we provide the following acknowledgements to the Commission: o Staff comments or changes to disclosure in response to Staff comments on the filings reviewed by the Staff do not foreclose the SEC from taking any action with respect to the filings; o Staff comments or changes to disclosure in response to Staff comments on the filings reviewed by the Staff does not relieve Registrant from its full responsibility for the adequacy and accuracy of the disclosure in the filings; and o Registrant may not assert Staff comments or changes to disclosure in response to Staff comments on the filings reviewed by the Staff as a defense in any proceeding initiated by the SEC. Please direct any inquiries regarding this filing to the undersigned at (650) 312-5824. Sincerely yours, /s/ David P. Goss David P. Goss Senior Associate General Counsel