Hillstream BioPharma, Inc.
1200 Route 22 East, Suite 2000
Bridgewater, NJ 08807
March 22, 2023
VIA EDGAR
United States Securities and Exchange Commission
100 F Street, N.E.
Washington, D.C. 20549
Attention: Arzhang Navai
| Re: | Hillstream BioPharma, Inc. | |
| Registration Statement on Form S-3 | ||
| File No. 333-270684 |
Ladies and Gentlemen:
Pursuant to Rule 461 of the General Rules and Regulations under the Securities Act of 1933, as amended, Hillstream BioPharma, Inc. (the “Company”) respectfully requests that the effective date of the registration statement referred to above be accelerated so that it will become effective at 4:30 p.m., Eastern Standard Time, on Friday, March 24, 2023, or as soon thereafter as possible.
Please notify Nazia Khan of Sheppard, Mullin, Richter & Hampton LLP, counsel to the Company, at (202) 747-2651 as soon as possible as to the time the Registration Statement has been declared effective pursuant to this acceleration request.
| HILLSTREAM BIOPHARMA, INC. | ||
| By: | /s/ Randy Milby | |
| Name: | Randy Milby | |
| Title: | Chief Executive Officer | |
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