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Selected Companies
|
| |
EV/2028E Revenue
Trading Multiple |
| |||
Agios Pharmaceuticals, Inc.
|
| | | | 0.4x | | |
Apellis Pharmaceuticals, Inc.
|
| | | | 1.6x | | |
Arcutis Biotherapeutics, Inc.
|
| | | | 2.5x | | |
Axsome Therapeutics, Inc.
|
| | | | 2.7x | | |
Geron Corporation
|
| | | | 0.8x | | |
ImmunityBio, Inc.
|
| | | | 3.1x | | |
Krystal Biotech, Inc.
|
| | | | 4.5x | | |
TG Therapeutics, Inc.
|
| | | | 5.2x | | |
Tarsus Pharmaceuticals, Inc.
|
| | | | 2.4x | | |
Travere Therapeutics, Inc.
|
| | | | 1.8x | | |
Date
Announced |
| |
Target
|
| |
Acquiror
|
| |
TV/4-Year
Forward Revenue |
| |||
5/10/2023
|
| | CTI BioPharma Corp. | | |
Swedish Orphan Biovitrum AB
|
| | | | 3.5x | | |
3/13/2023
|
| | Provention Bio, Inc. | | | Sanofi S.A. | | | | | 5.2x | | |
8/8/2022
|
| |
Global Blood Therapeutics, Inc.
|
| | Pfizer Inc. | | | | | 5.0x | | |
8/4/2022
|
| | ChemoCentryx, Inc. | | | Amgen Inc. | | | | | 4.1x | | |
1/19/2022
|
| | Zogenix, Inc. | | | UCB S.A. | | | | | 2.3x | | |
2/3/2021
|
| | GW Pharmaceuticals plc | | | Jazz Pharmaceuticals plc | | | | | 3.4x | | |
| | |
2025E
|
| |
2026E
|
| |
2027E
|
| |
2028E
|
| |
2029E
|
| |
2030E
|
| |
2031E
|
| |
2032E
|
| |
2033E
|
| |
2034E
|
| ||||||||||||||||||||||||||||||
Net Revenue
|
| | | $ | 480 | | | | | $ | 817 | | | | | $ | 1,176 | | | | | $ | 1,388 | | | | | $ | 1,461 | | | | | $ | 1,547 | | | | | $ | 1,645 | | | | | $ | 1,745 | | | | | $ | 1,821 | | | | | $ | 1,873 | | |
Gross Profit
|
| | | $ | 397 | | | | | $ | 657 | | | | | $ | 974 | | | | | $ | 1,131 | | | | | $ | 1,193 | | | | | $ | 1,282 | | | | | $ | 1,371 | | | | | $ | 1,454 | | | | | $ | 1,479 | | | | | $ | 1,527 | | |
EBIT(1) | | | | $ | (147) | | | | | $ | 121 | | | | | $ | 408 | | | | | $ | 560 | | | | | $ | 618 | | | | | $ | 812 | | | | | $ | 938 | | | | | $ | 1,051 | | | | | $ | 1,103 | | | | | $ | 1,135 | | |
| | |
2035E
|
| |
2036E
|
| |
2037E
|
| |
2038E
|
| |
2039E
|
| |
2040E
|
| |
2041E
|
| |
2042E
|
| |
2043E
|
| |||||||||||||||||||||||||||
Net Revenue
|
| | | $ | 1,896 | | | | | $ | 1,839 | | | | | $ | 1,817 | | | | | $ | 1,849 | | | | | $ | 1,894 | | | | | $ | 1,946 | | | | | $ | 1,995 | | | | | $ | 2,006 | | | | | $ | 1,456 | | |
Gross Profit
|
| | | $ | 1,584 | | | | | $ | 1,544 | | | | | $ | 1,530 | | | | | $ | 1,557 | | | | | $ | 1,592 | | | | | $ | 1,623 | | | | | $ | 1,672 | | | | | $ | 1,677 | | | | | $ | 1,259 | | |
EBIT(1) | | | | $ | 1,175 | | | | | $ | 1,144 | | | | | $ | 1,131 | | | | | $ | 1,152 | | | | | $ | 1,176 | | | | | $ | 1,195 | | | | | $ | 1,232 | | | | | $ | 1,230 | | | | | $ | 928 | | |
| | |
2025E
|
| |
2026E
|
| |
2027E
|
| |
2028E
|
| |
2029E
|
| |
2030E
|
| |
2031E
|
| |
2032E
|
| |
2033E
|
| |
2034E
|
| ||||||||||||||||||||||||||||||
EBIT(1) | | | | $ | (147) | | | | | $ | 121 | | | | | $ | 408 | | | | | $ | 560 | | | | | $ | 618 | | | | | $ | 812 | | | | | $ | 938 | | | | | $ | 1,051 | | | | | $ | 1,103 | | | | | $ | 1,135 | | |
Less: Tax Expense(2)
|
| | | | — | | | | | $ | (27) | | | | | $ | (90) | | | | | $ | (123) | | | | | $ | (136) | | | | | $ | (179) | | | | | $ | (206) | | | | | $ | (231) | | | | | $ | (243) | | | | | $ | (250) | | |
Plus: Depreciation & Amortization
|
| | | $ | 1 | | | | | $ | 2 | | | | | $ | 4 | | | | | $ | 6 | | | | | $ | 9 | | | | | $ | 11 | | | | | $ | 14 | | | | | $ | 17 | | | | | $ | 20 | | | | | $ | 23 | | |
| | |
2025E
|
| |
2026E
|
| |
2027E
|
| |
2028E
|
| |
2029E
|
| |
2030E
|
| |
2031E
|
| |
2032E
|
| |
2033E
|
| |
2034E
|
| ||||||||||||||||||||||||||||||
Less: Capital Expenditures
|
| | | $ | (10) | | | | | $ | (20) | | | | | $ | (29) | | | | | $ | (35) | | | | | $ | (37) | | | | | $ | (39) | | | | | $ | (41) | | | | | $ | (44) | | | | | $ | (46) | | | | | $ | (47) | | |
Less: Changes in Net Working
Capital |
| | | $ | (36) | | | | | $ | (62) | | | | | $ | (54) | | | | | $ | (32) | | | | | $ | (11) | | | | | $ | (13) | | | | | $ | (15) | | | | | $ | (15) | | | | | $ | (11) | | | | | $ | (8) | | |
Unlevered Free Cash Flow(3)
|
| | | $ | (192) | | | | | $ | 14 | | | | | $ | 239 | | | | | $ | 376 | | | | | $ | 443 | | | | | $ | 593 | | | | | $ | 689 | | | | | $ | 778 | | | | | $ | 823 | | | | | $ | 854 | | |
| | |
2035E
|
| |
2036E
|
| |
2037E
|
| |
2038E
|
| |
2039E
|
| |
2040E
|
| |
2041E
|
| |
2042E
|
| |
2043E
|
| |||||||||||||||||||||||||||
EBIT(1) | | | | $ | 1,175 | | | | | $ | 1,144 | | | | | $ | 1,131 | | | | | $ | 1,152 | | | | | $ | 1,176 | | | | | $ | 1,195 | | | | | $ | 1,232 | | | | | $ | 1,230 | | | | | $ | 928 | | |
Less: Tax Expense(2)
|
| | | $ | (258) | | | | | $ | (252) | | | | | $ | (249) | | | | | $ | (253) | | | | | $ | (259) | | | | | $ | (263) | | | | | $ | (271) | | | | | $ | (271) | | | | | $ | (204) | | |
Plus: Depreciation & Amortization
|
| | | $ | 26 | | | | | $ | 29 | | | | | $ | 32 | | | | | $ | 35 | | | | | $ | 39 | | | | | $ | 41 | | | | | $ | 43 | | | | | $ | 45 | | | | | $ | 45 | | |
Less: Capital Expenditures
|
| | | $ | (47) | | | | | $ | (46) | | | | | $ | (45) | | | | | $ | (46) | | | | | $ | (47) | | | | | $ | (49) | | | | | $ | (50) | | | | | $ | (50) | | | | | $ | (36) | | |
Less: Changes in Net Working Capital
|
| | | $ | (3) | | | | | $ | 9 | | | | | $ | 3 | | | | | $ | (5) | | | | | $ | (7) | | | | | $ | (8) | | | | | $ | (7) | | | | | $ | (2) | | | | | $ | 83 | | |
Unlevered Free Cash Flow(3)
|
| | | $ | 892 | | | | | $ | 885 | | | | | $ | 873 | | | | | $ | 883 | | | | | $ | 902 | | | | | $ | 917 | | | | | $ | 947 | | | | | $ | 952 | | | | | $ | 815 | | |
| | |
2025E
|
| |
2026E
|
| |
2027E
|
| |
2028E
|
| |
2029E
|
| |
2030E
|
| |
2031E
|
| |
2032E
|
| |
2033E
|
| |
2034E
|
| ||||||||||||||||||||||||||||||
Net Revenue
|
| | | $ | 471 | | | | | $ | 722 | | | | | $ | 1,089 | | | | | $ | 1,315 | | | | | $ | 1,408 | | | | | $ | 1,467 | | | | | $ | 1,539 | | | | | $ | 1,615 | | | | | $ | 1,668 | | | | | $ | 1,699 | | |
Gross Profit
|
| | | $ | 417 | | | | | $ | 599 | | | | | $ | 877 | | | | | $ | 1,078 | | | | | $ | 1,188 | | | | | $ | 1,191 | | | | | $ | 1,295 | | | | | $ | 1,359 | | | | | $ | 1,412 | | | | | $ | 1,436 | | |
EBIT(1) | | | | $ | (137) | | | | | $ | 39 | | | | | $ | 302 | | | | | $ | 489 | | | | | $ | 593 | | | | | $ | 725 | | | | | $ | 870 | | | | | $ | 969 | | | | | $ | 1,052 | | | | | $ | 1,064 | | |
| | |
2035E
|
| |
2036E
|
| |
2037E
|
| |
2038E
|
| |
2039E
|
| |
2040E
|
| |
2041E
|
| |
2042E
|
| |
2043E
|
| |
2044E
|
| ||||||||||||||||||||||||||||||
Net Revenue
|
| | | $ | 1,706 | | | | | $ | 1,608 | | | | | $ | 1,616 | | | | | $ | 1,651 | | | | | $ | 1,691 | | | | | $ | 1,735 | | | | | $ | 1,781 | | | | | $ | 1,786 | | | | | $ | 1,257 | | | | | $ | 433 | | |
Gross Profit
|
| | | $ | 1,398 | | | | | $ | 1,368 | | | | | $ | 1,376 | | | | | $ | 1,405 | | | | | $ | 1,438 | | | | | $ | 1,463 | | | | | $ | 1,511 | | | | | $ | 1,512 | | | | | $ | 1,105 | | | | | $ | 406 | | |
EBIT(1) | | | | $ | 1,012 | | | | | $ | 996 | | | | | $ | 1,000 | | | | | $ | 1,021 | | | | | $ | 1,044 | | | | | $ | 1,058 | | | | | $ | 1,093 | | | | | $ | 1,088 | | | | | $ | 801 | | | | | $ | 300 | | |
| | |
2025E
|
| |
2026E
|
| |
2027E
|
| |
2028E
|
| |
2029E
|
| |
2030E
|
| |
2031E
|
| |
2032E
|
| |
2033E
|
| |
2034E
|
| ||||||||||||||||||||||||||||||
EBIT(1) | | | | $ | (137) | | | | | $ | 39 | | | | | $ | 302 | | | | | $ | 489 | | | | | $ | 593 | | | | | $ | 725 | | | | | $ | 870 | | | | | $ | 969 | | | | | $ | 1,052 | | | | | $ | 1,064 | | |
Less: Tax Expense(2)
|
| | | | — | | | | | $ | (9) | | | | | $ | (67) | | | | | $ | (107) | | | | | $ | (130) | | | | | $ | (159) | | | | | $ | (191) | | | | | $ | (213) | | | | | $ | (231) | | | | | $ | (234) | | |
| | |
2025E
|
| |
2026E
|
| |
2027E
|
| |
2028E
|
| |
2029E
|
| |
2030E
|
| |
2031E
|
| |
2032E
|
| |
2033E
|
| |
2034E
|
| ||||||||||||||||||||||||||||||
Plus: Depreciation & Amortization
|
| | | $ | 1 | | | | | $ | 2 | | | | | $ | 4 | | | | | $ | 6 | | | | | $ | 8 | | | | | $ | 11 | | | | | $ | 13 | | | | | $ | 16 | | | | | $ | 19 | | | | | $ | 21 | | |
Less: Capital Expenditures
|
| | | $ | (8) | | | | | $ | (18) | | | | | $ | (27) | | | | | $ | (33) | | | | | $ | (35) | | | | | $ | (37) | | | | | $ | (38) | | | | | $ | (40) | | | | | $ | (42) | | | | | $ | (42) | | |
Less: Changes in Net Working Capital
|
| | | $ | (22) | | | | | $ | (60) | | | | | $ | (55) | | | | | $ | (34) | | | | | $ | (14) | | | | | $ | (9) | | | | | $ | (11) | | | | | $ | (11) | | | | | $ | (8) | | | | | $ | (5) | | |
Unlevered Free Cash Flow(3)
|
| | | $ | (167) | | | | | $ | (46) | | | | | $ | 157 | | | | | $ | 320 | | | | | $ | 421 | | | | | $ | 530 | | | | | $ | 642 | | | | | $ | 720 | | | | | $ | 789 | | | | | $ | 804 | | |
| | |
2035E
|
| |
2036E
|
| |
2037E
|
| |
2038E
|
| |
2039E
|
| |
2040E
|
| |
2041E
|
| |
2042E
|
| |
2043E
|
| |
2044E
|
| ||||||||||||||||||||||||||||||
EBIT(1) | | | | $ | 1,012 | | | | | $ | 996 | | | | | $ | 1,000 | | | | | $ | 1,021 | | | | | $ | 1,044 | | | | | $ | 1,058 | | | | | $ | 1,093 | | | | | $ | 1,088 | | | | | $ | 801 | | | | | $ | 300 | | |
Less: Tax Expense(2)
|
| | | $ | (223) | | | | | $ | (219) | | | | | $ | (220) | | | | | $ | (225) | | | | | $ | (230) | | | | | $ | (233) | | | | | $ | (241) | | | | | $ | (239) | | | | | $ | (176) | | | | | $ | (66) | | |
Plus: Depreciation & Amortization
|
| | | $ | 24 | | | | | $ | 27 | | | | | $ | 30 | | | | | $ | 32 | | | | | $ | 35 | | | | | $ | 38 | | | | | $ | 39 | | | | | $ | 40 | | | | | $ | 40 | | | | | $ | 39 | | |
Less: Capital
Expenditures |
| | | $ | (43) | | | | | $ | (40) | | | | | $ | (40) | | | | | $ | (41) | | | | | $ | (42) | | | | | $ | (43) | | | | | $ | (45) | | | | | $ | (45) | | | | | $ | (31) | | | | | $ | (11) | | |
Less: Changes in Net Working Capital
|
| | | $ | (1) | | | | | $ | 15 | | | | | $ | (1) | | | | | $ | (5) | | | | | $ | (6) | | | | | $ | (7) | | | | | $ | (7) | | | | | $ | (1) | | | | | $ | 79 | | | | | $ | 124 | | |
Unlevered Free Cash Flow(3)
|
| | | $ | 770 | | | | | $ | 779 | | | | | $ | 768 | | | | | $ | 783 | | | | | $ | 801 | | | | | $ | 813 | | | | | $ | 841 | | | | | $ | 844 | | | | | $ | 713 | | | | | $ | 385 | | |
Name
|
| |
Position
|
|
Saqib Islam, J.D. | | | Chief Executive Officer | |
Francis I. Perier, Jr., M.B.A. | | | Chief Financial Officer | |
Badreddin Edris, Ph.D. | | | Chief Operating Officer | |
Bhavesh Ashar, M.B.A. | | | Chief Commercial Officer | |
James Cassidy, M.D., Ph.D. | | | Chief Medical Officer | |
Daniel Pichl | | | Chief People Officer | |
Herschel S. Weinstein, J.D. | | | General Counsel and Secretary | |
Tai-An Lin, Ph.D. | | | Chief Scientific Officer | |
Name
|
| | | |
Carlos Albán | | | ||
Alan Fuhrman | | | ||
Julie Hambleton, M.D. | | | ||
Freda Lewis-Hall, M.D., DFAPA | | | ||
Daniel S. Lynch, M.B.A. | | | ||
Martin Mackay, Ph.D. | | |
Name
|
| |
Number of
Company Shares Owned |
| |||
Saqib Islam, J.D.
|
| | | | 602,880 | | |
Francis I. Perier, Jr. , M.B.A.
|
| | | | 28,330 | | |
Badreddin Edris, Ph.D.
|
| | | | 102,781 | | |
Bhavesh Ashar, M.B.A.
|
| | | | 19,305 | | |
James Cassidy, M.D., Ph.D.
|
| | | | 33,969 | | |
Daniel Pichl
|
| | | | 15,982 | | |
Herschel S. Weinstein, J.D.
|
| | | | 22,333 | | |
Tai-An Lin, Ph.D.
|
| | | | 6,486 | | |
Carlos Albán
|
| | | | 15,381 | | |
Alan Fuhrman
|
| | | | 14,667 | | |
Julie Hambleton, M.D.
|
| | | | 4,095 | | |
Freda Lewis-Hall, M.D., DFAPA
|
| | | | 14,667 | | |
Daniel S. Lynch, M.B.A.
|
| | | | 82,944 | | |
Martin Mackay, Ph.D.
|
| | | | — | | |
| | |
Vested Company Options
|
| |
Unvested Company Options
|
| ||||||||||||||||||
Name
|
| |
Number of
Shares (#) |
| |
Value
($) |
| |
Number of
Shares (#) |
| |
Value
($) |
| ||||||||||||
Executive Officers | | | | | | | | | | | | | | | | | | | | | | | | | |
Saqib Islam, J.D.
|
| | | | 2,041,632 | | | | | | 51,352,830 | | | | | | 415,930 | | | | | | 3,931,556 | | |
Francis I. Perier, Jr., M.B.A.
|
| | | | 668,558 | | | | | | 16,585,182 | | | | | | 133,406 | | | | | | 1,478,547 | | |
Badreddin Edris, Ph.D.
|
| | | | 611,768 | | | | | | 11,271,440 | | | | | | 265,950 | | | | | | 2,913,518 | | |
Bhavesh Ashar, M.B.A.
|
| | | | 260,558 | | | | | | 2,315,345 | | | | | | 167,767 | | | | | | 1,889,310 | | |
James Cassidy, M.D., Ph.D.
|
| | | | 209,188 | | | | | | 1,770,774 | | | | | | 167,995 | | | | | | 1,733,281 | | |
Daniel Pichl
|
| | | | 176,508 | | | | | | 712,956 | | | | | | 136,537 | | | | | | 1,518,352 | | |
Herschel S. Weinstein, J.D.
|
| | | | 292,393 | | | | | | 3,013,240 | | | | | | 131,348 | | | | | | 1,482,260 | | |
Tai-An Lin, Ph.D.
|
| | | | 36,374 | | | | | | 768,173 | | | | | | 73,872 | | | | | | 1,256,809 | | |
Non-Employee Directors | | | | | | | | | | | | | | | | | | | | | | | | | |
Carlos Albán
|
| | | | 54,474 | | | | | | 744,837 | | | | | | 1,676 | | | | | | 30,285 | | |
Alan Fuhrman
|
| | | | 85,753 | | | | | | 1,343,973 | | | | | | — | | | | | | — | | |
Julie Hambleton, M.D.
|
| | | | 49,200 | | | | | | 336,194 | | | | | | — | | | | | | — | | |
Freda Lewis-Hall, M.D., DFAPA
|
| | | | 85,753 | | | | | | 1,343,973 | | | | | | — | | | | | | — | | |
Daniel S. Lynch, M.B.A.
|
| | | | 324,576 | | | | | | 12,023,551 | | | | | | — | | | | | | — | | |
Martin Mackay, Ph.D.
|
| | | | 7,361 | | | | | | 75,082 | | | | | | 22,084 | | | | | | 225,256 | | |
| | |
Company RSUs
|
| |||||||||
Name
|
| |
Number of
Shares (#) |
| |
Value
($) |
| ||||||
Executive Officers | | | | | | | | | | | | | |
Saqib Islam, J.D.
|
| | | | 162,414 | | | | | | 7,633,458 | | |
Francis I. Perier, Jr., M.B.A.
|
| | | | 32,559 | | | | | | 1,530,273 | | |
Badreddin Edris, Ph.D.
|
| | | | 66,931 | | | | | | 3,145,757 | | |
Bhavesh Ashar, M.B.A.
|
| | | | 42,748 | | | | | | 2,009,156 | | |
James Cassidy, M.D., Ph.D.
|
| | | | 47,762 | | | | | | 2,244,814 | | |
Daniel Pichl
|
| | | | 34,780 | | | | | | 1,634,660 | | |
Herschel S. Weinstein, J.D.
|
| | | | 32,906 | | | | | | 1,546,582 | | |
Tai-An Lin, Ph.D.
|
| | | | 26,553 | | | | | | 1,247,991 | | |
Non-Employee Directors | | | | | | | | | | | | | |
Carlos Albán
|
| | | | 13,480 | | | | | | 633,560 | | |
Alan Fuhrman
|
| | | | 10,060 | | | | | | 472,820 | | |
Julie Hambleton, M.D.
|
| | | | 10,060 | | | | | | 472,820 | | |
Freda Lewis-Hall, M.D., DFAPA
|
| | | | 10,060 | | | | | | 472,820 | | |
Daniel S. Lynch, M.B.A.
|
| | | | 10,060 | | | | | | 472,820 | | |
Martin Mackay, Ph.D.
|
| | | | 20,023 | | | | | | 941,081 | | |
| | |
Company PSUs
|
| |||||||||
Name
|
| |
Number of
Shares (#) |
| |
Value
($) |
| ||||||
Executive Officers | | | | | | | | | | | | | |
Saqib Islam, J.D.
|
| | | | 579,749 | | | | | | 27,248,203 | | |
Francis I. Perier, Jr., M.B.A.
|
| | | | 14,724 | | | | | | 692,028 | | |
Badreddin Edris, Ph.D.
|
| | | | 33,778 | | | | | | 1,587,566 | | |
Bhavesh Ashar, M.B.A.
|
| | | | 21,654 | | | | | | 1,017,738 | | |
James Cassidy, M.D., Ph.D.
|
| | | | 21,654 | | | | | | 1,017,738 | | |
Daniel Pichl
|
| | | | 16,023 | | | | | | 753,081 | | |
Herschel S. Weinstein, J.D.
|
| | | | 15,157 | | | | | | 712,379 | | |
Tai-An Lin, Ph.D.
|
| | | | 8,661 | | | | | | 407,067 | | |
| | |
Company PSUs
|
| |||||||||
Name
|
| |
Number of
Shares (#) |
| |
Value
($) |
| ||||||
Non-Employee Directors | | | | | | | | | | | | | |
Carlos Albán
|
| | | | — | | | | | | — | | |
Alan Fuhrman
|
| | | | — | | | | | | — | | |
Julie Hambleton, M.D.
|
| | | | — | | | | | | — | | |
Freda Lewis-Hall, M.D., DFAPA
|
| | | | — | | | | | | — | | |
Daniel S. Lynch, M.B.A.
|
| | | | — | | | | | | — | | |
Martin Mackay, Ph.D.
|
| | | | — | | | | | | — | | |
Name
|
| |
Cash
($)(1) |
| |
Equity
($)(2) |
| |
Perquisites/Benefits
($)(3) |
| |
Total
($) |
| ||||||||||||
Saqib Islam, J.D.
|
| | | | 2,800,000 | | | | | | 38,813,217 | | | | | | 75,378 | | | | | | 41,688,595 | | |
Francis I. Perier, Jr., M.B.A.
|
| | | | 765,600 | | | | | | 3,700,848 | | | | | | 37,689 | | | | | | 4,504,137 | | |
Bhavesh Ashar, M.B.A.
|
| | | | 798,950 | | | | | | 4,916,204 | | | | | | 37,689 | | | | | | 5,752,843 | | |
Badreddin Edris, Ph.D.
|
| | | | 1,009,050 | | | | | | 7,646,841 | | | | | | 37,689 | | | | | | 8,693,580 | | |
James Cassidy, M.D., Ph.D.
|
| | | | 798,950 | | | | | | 4,995,833 | | | | | | 39,813 | | | | | | 5,834,596 | | |
| | |
Shares beneficially owned
|
| |||||||||
Name and address of beneficial owner(1)
|
| |
Number
|
| |
Percentage
|
| ||||||
Greater than 5% Stockholders: | | | | | | | | | | | | | |
FMR LLC(2)
|
| | | | 11,204,799 | | | | | | 14.87% | | |
The Vanguard Group(3)
|
| | | | 7,082,581 | | | | | | 9.40% | | |
BlackRock, Inc.(4)
|
| | | | 6,246,071 | | | | | | 8.29% | | |
Named Executive Officers and Directors: | | | | | | | | | | | | | |
Saqib Islam, J.D.(5)
|
| | | | 2,680,496 | | | | | | 3.46% | | |
Badreddin Edris, Ph.D.(6)
|
| | | | 736,231 | | | | | | * | | |
Francis I. Perier, Jr., M.B.A.(7)
|
| | | | 708,474 | | | | | | * | | |
Daniel S. Lynch, M.B.A.(8)
|
| | | | 407,520 | | | | | | * | | |
Bhavesh Ashar, M.B.A.(9)
|
| | | | 293,877 | | | | | | * | | |
James Cassidy, M.D., Ph.D.(10)
|
| | | | 260,763 | | | | | | * | | |
Freda Lewis-Hall, M.D., DFAPA(11)
|
| | | | 100,420 | | | | | | * | | |
Alan Fuhrman(12)
|
| | | | 100,420 | | | | | | * | | |
Carlos Albán(13)
|
| | | | 70,693 | | | | | | * | | |
Julie Hambleton, M.D.(14)
|
| | | | 53,295 | | | | | | * | | |
Martin Mackay, Ph.D.(15)
|
| | | | 8,997 | | | | | | * | | |
All executive officers and directors as a group (14 persons)(16)
|
| | | | 5,997,910 | | | | | | 7.96% | | |
| | |
Page
|
| |||
ARTICLE I
The Merger; Closing; Certificate of Merger and Effective Time
|
| ||||||
| | | | A-1 | | | |
| | | | A-1 | | | |
| | | | A-1 | | | |
ARTICLE II
Certificate of Incorporation and Bylaws of the Surviving Corporation;
Directors and Officers of the Surviving Corporation |
| ||||||
| | | | A-2 | | | |
| | | | A-2 | | | |
| | | | A-2 | | | |
| | | | A-2 | | | |
ARTICLE III
Effect of the Merger on Capital Stock; Treatment of Equity Awards;
Delivery of Merger Consideration |
| ||||||
| | | | A-2 | | | |
| | | | A-2 | | | |
| | | | A-4 | | | |
| | | | A-7 | | | |
ARTICLE IV
Representations and Warranties of the Company
|
| ||||||
| | | | A-8 | | | |
| | | | A-8 | | | |
| | | | A-9 | | | |
| | | | A-10 | | | |
| | | | A-11 | | | |
| | | | A-12 | | | |
| | | | A-12 | | | |
| | | | A-12 | | | |
| | | | A-13 | | | |
| | | | A-14 | | | |
| | | | A-14 | | | |
| | | | A-14 | | | |
| | | | A-14 | | | |
| | | | A-16 | | | |
| | | | A-17 | | | |
| | | | A-18 | | | |
| | | | A-18 | | | |
| | | | A-20 | | |
| | |
Page
|
| |||
| | | | A-20 | | | |
| | | | A-22 | | | |
| | | | A-22 | | | |
| | | | A-23 | | | |
| | | | A-24 | | | |
| | | | A-24 | | | |
| | | | A-25 | | | |
| | | | A-25 | | | |
| | | | A-25 | | | |
| | | | A-25 | | | |
ARTICLE V
Representations and Warranties of Parent and Merger Sub
|
| ||||||
| | | | A-26 | | | |
| | | | A-26 | | | |
| | | | A-26 | | | |
| | | | A-26 | | | |
| | | | A-27 | | | |
| | | | A-27 | | | |
| | | | A-27 | | | |
| | | | A-27 | | | |
| | | | A-27 | | | |
| | | | A-27 | | | |
ARTICLE VI
Covenants
|
| ||||||
| | | | A-28 | | | |
| | | | A-31 | | | |
| | | | A-32 | | | |
| | | | A-35 | | | |
| | | | A-36 | | | |
| | | | A-37 | | | |
| | | | A-38 | | | |
| | | | A-39 | | | |
| | | | A-39 | | | |
| | | | A-40 | | | |
| | | | A-40 | | | |
| | | | A-41 | | | |
| | | | A-43 | | | |
| | | | A-44 | | | |
| | | | A-44 | | | |
| | | | A-44 | | | |
| | | | A-45 | | | |
| | | | A-45 | | |
| | |
Page
|
| |||
ARTICLE VII
Conditions
|
| ||||||
| | | | A-45 | | | |
| | | | A-46 | | | |
| | | | A-46 | | | |
ARTICLE VIII
Termination
|
| ||||||
| | | | A-47 | | | |
| | | | A-47 | | | |
| | | | A-48 | | | |
| | | | A-48 | | | |
| | | | A-48 | | | |
ARTICLE IX
Miscellaneous and General
|
| ||||||
| | | | A-50 | | | |
| | | | A-50 | | | |
| | | | A-51 | | | |
| | | | A-51 | | | |
| | | | A-51 | | | |
| | | | A-52 | | | |
| | | | A-52 | | | |
| | | | A-53 | | | |
| | | | A-53 | | | |
| | | | A-53 | | | |
| | | | A-53 | | | |
| | | | A-54 | | | |
| | | | A-54 | | |
| Annexes | | | | |
| Annex A | | | Certain Definitions | |
| Annex B | | | Form of Certificate of Incorporation of the Surviving Corporation | |