[Letterhead of Nuo Therapeutics, Inc.]
January 9, 2017
VIA EDGAR
Securities and Exchange Commission
Division of Corporation Finance
100 F Street, N.E.
Washington, D.C. 20549
| Re: | Nuo Therapeutics, Inc. |
Registration Statement on Form S-1/A
Filed December 23, 2016
File No. 333-214748
Ladies and Gentlemen:
In accordance with Rule 461 under the Securities Act of 1933, as amended, the undersigned respectfully requests that the effective date for the Registration Statement referred to above be accelerated so that it will be declared effective at 9:00 AM on January 11, 2017, or as soon thereafter as is practicable.
| Very truly yours, | |||
| Nuo Therapeutics, Inc. | |||
| By: | /s/ David E. Jorden | ||
| Name: | David E. Jorden | ||
| Title: | Chief Executive Officer and Chief Financial Officer | ||