(Name
of Issuer)
Common
Stock, par value $0.001 per share
|
||
(Title
of Class of Securities)
|
||
45884X103
|
||
(CUSIP
Number)
January
16, 2009
|
||
(Date
of Event which Requires Filing of this Statement)
|
CUSIP NO.
|
45884X103
|
1 |
NAMES
OF REPORTING PERSONS
I.R.S.
IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES
ONLY): |
||||
Felix J. Baker
|
|||||
2 |
CHECK
THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE
INSTRUCTIONS):
|
||||
(a) o | |||||
(b) o | |||||
3 |
SEC
USE ONLY:
|
||||
4 |
CITIZENSHIP
OR PLACE OF ORGANIZATION:
|
||||
United States | |||||
5 |
SOLE
VOTING POWER:
|
||||
NUMBER
OF
|
-0- | ||||
SHARES | 6 |
SHARED
VOTING POWER:
|
|||
BENEFICIALLY | |||||
OWNED BY | 2,431,030 | ||||
EACH | 7 |
SOLE
DISPOSITIVE POWER:
|
|||
REPORTING | |||||
PERSON | -0- | ||||
WITH: | 8 |
SHARED
DISPOSITIVE POWER:
|
|||
2,431,030 | |||||
9 |
AGGREGATE
AMOUNT BENEFICIALLY OWNED BY EACH REPORTING
PERSON:
|
||||
2,431,030 | |||||
10 |
CHECK
IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE
INSTRUCTIONS):
|
||||
o | |||||
11 |
PERCENT
OF CLASS REPRESENTED BY AMOUNT IN ROW (9):
|
||||
6.0% | |||||
12 |
TYPE
OF REPORTING PERSON (SEE INSTRUCTIONS):
|
||||
IN |
CUSIP NO.
|
45884X103
|
1 |
NAMES
OF REPORTING PERSONS
I.R.S.
IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES
ONLY): |
||||
Julian C. Baker
|
|||||
2 |
CHECK
THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE
INSTRUCTIONS):
|
||||
(a) o | |||||
(b) o | |||||
3 |
SEC
USE ONLY:
|
||||
4 |
CITIZENSHIP
OR PLACE OF ORGANIZATION:
|
||||
United States | |||||
5 |
SOLE
VOTING POWER:
|
||||
NUMBER
OF
|
-0- | ||||
SHARES | 6 |
SHARED
VOTING POWER:
|
|||
BENEFICIALLY | |||||
OWNED BY | 2,431,030 | ||||
EACH | 7 |
SOLE
DISPOSITIVE POWER:
|
|||
REPORTING | |||||
PERSON | -0- | ||||
WITH: | 8 |
SHARED
DISPOSITIVE POWER:
|
|||
2,431,030 | |||||
9 |
AGGREGATE
AMOUNT BENEFICIALLY OWNED BY EACH REPORTING
PERSON:
|
||||
2,431,030 | |||||
10 |
CHECK
IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE
INSTRUCTIONS):
|
||||
o | |||||
11 |
PERCENT
OF CLASS REPRESENTED BY AMOUNT IN ROW (9):
|
||||
6.0% | |||||
12 |
TYPE
OF REPORTING PERSON (SEE INSTRUCTIONS):
|
||||
IN |
Item
1(a)
|
Name
of Issuer:
|
Item
1(b)
|
Address
of Issuer’s Principal Executive
Offices:
|
Item
2(a)
|
Name
of Person Filing:
|
Item
2(b)
|
Address
of Principal Business Office or, if None,
Residence:
|
Name
|
Business Address
|
||
Felix
J. Baker
|
667
Madison Avenue
New
York, NY 10065
|
||
Julian
C. Baker
|
667
Madison Avenue
New
York, NY 10065
|
Item
2(c)
|
Citizenship:
|
Item
2(d)
|
Title
of Class of Securities:
|
Item
2(e)
|
CUSIP
Number:
|
Item
3.
|
If
this statement is filed pursuant to §§240.13d-1(b) or (c), check whether
the person filing is
a: N/A
|
Item
4.
|
Ownership.
|
Name
|
Number
of Shares
|
Percent
of Class
Outstanding
|
||||||
Baker
Bros. Investments I, L.P.
|
14,238 | 0.0 | % | |||||
Baker
Bros. Investments II, L.P.
|
827 | 0.0 | % | |||||
667,
L.P.
|
595,271 | 1.5 | % | |||||
Baker
Brothers Life Sciences, L.P.
|
1,758,994 | 4.4 | % | |||||
14159,
L.P.
|
48,495 | 0.1 | % | |||||
Baker/Tisch
Investments, L.P.
|
12.770 | 0.0 | % | |||||
FBB
Associates
|
435 | 0.0 | % | |||||
Total
|
2,431,030 | 6.0 | % |
Item
5.
|
Ownership
of Five Percent or Less of a Class.
|
Item
6.
|
Ownership
of More than Five Percent on Behalf of Another
Person.
|
Item
7.
|
Identification
and Classification of the Subsidiary Which Acquired the Security Being
Reported on by the Parent Holding Company or Control
Person.
|
Item
8.
|
Identification
and Classification of Members of the
Group.
|
Item
9.
|
Notice
of Dissolution of Group.
|
Item
10.
|
Certification.
|
/s/
Felix J. Baker
|
|
Felix
J. Baker
|
|
/s/
Julian C. Baker
|
|
Julian
C. Baker
|
|
/s/
Felix J. Baker
|
|
Felix
J. Baker
|
|
/s/
Julian C. Baker
|
|
Julian
C. Baker
|
|