BAKER BROS. ADVISORS LP
≥5% Ownership
| 4 | 34 | 06/24/2025 | 06/20/2025 |
| 4 | 34 | 06/12/2025 | 06/10/2025 |
| 4 | 34 | 06/12/2025 | 06/10/2025 |
| 4 | 34 | 06/05/2025 | 06/03/2025 |
| 4 | 34 | 06/05/2025 | 06/03/2025 |
| 3 | 34 | 06/05/2025 | 06/03/2025 |
| 4 | 34 | 06/02/2025 | 05/29/2025 |
| 4 | 34 | 05/22/2025 | 05/21/2025 |
| 4 | 34 | 05/19/2025 | 05/15/2025 |
| 4 | 34 | 04/02/2025 | 03/31/2025 |